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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM12
All Species:
17.27
Human Site:
S814
Identified Species:
38
UniProt:
O43184
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43184
NP_003465.3
909
99542
S814
L
N
V
P
Q
P
Q
S
T
Q
R
V
L
P
P
Chimpanzee
Pan troglodytes
XP_508106
914
100282
S819
L
N
V
P
Q
P
Q
S
T
Q
R
V
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001087980
909
99411
S814
L
S
V
P
Q
P
Q
S
T
Q
R
V
L
P
P
Dog
Lupus familis
XP_546274
909
99674
A812
A
A
R
N
S
P
G
A
G
P
Q
V
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61824
903
98582
S810
R
A
V
P
Q
L
Q
S
P
Q
R
V
L
L
P
Rat
Rattus norvegicus
Q9QYV0
816
88034
C728
A
R
L
H
Q
R
L
C
Q
L
K
G
S
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
S758
D
V
R
S
S
P
G
S
S
P
R
V
E
A
K
Chicken
Gallus gallus
NP_001136322
922
101009
T827
H
H
V
P
Q
L
K
T
P
Q
R
V
L
P
P
Frog
Xenopus laevis
O42596
935
104143
I822
C
S
I
P
H
Y
S
I
S
Q
N
I
S
L
F
Zebra Danio
Brachydanio rerio
XP_001921148
773
83366
P685
T
Y
T
H
T
P
A
P
A
A
P
S
T
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999635
1023
111059
R887
V
P
V
P
K
G
I
R
V
A
P
K
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
43.7
N.A.
80.3
35.5
N.A.
43.3
71.5
28.3
56.7
N.A.
N.A.
N.A.
N.A.
35.8
Protein Similarity:
100
95.9
97.1
59.4
N.A.
88.1
50.3
N.A.
58
82.4
44.4
65.2
N.A.
N.A.
N.A.
N.A.
51.2
P-Site Identity:
100
100
93.3
13.3
N.A.
66.6
6.6
N.A.
26.6
60
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
26.6
N.A.
66.6
20
N.A.
33.3
80
40
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
0
0
0
0
10
10
10
19
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
19
0
10
0
0
10
0
0
10
% G
% His:
10
10
0
19
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
10
10
0
0
10
% K
% Leu:
28
0
10
0
0
19
10
0
0
10
0
0
46
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
10
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
0
64
0
55
0
10
19
19
19
0
10
46
46
% P
% Gln:
0
0
0
0
55
0
37
0
10
55
10
0
0
0
0
% Q
% Arg:
10
10
19
0
0
10
0
10
0
0
55
0
0
19
10
% R
% Ser:
0
19
0
10
19
0
10
46
19
0
0
10
19
10
10
% S
% Thr:
10
0
10
0
10
0
0
10
28
0
0
0
10
0
0
% T
% Val:
10
10
55
0
0
0
0
0
10
0
0
64
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _